Avaliação microscópica do processo de cicalrização em feridas induzidas experimentalmente, tratadas com Aloe vera em ovinos

Abstract

The general objective of this work was to microscopically evaluate the effectiveness of Aloe vera in the healing of skin wounds induced experimentally in sheep. Fifteen castrated males, crossbred, aged between 6 and 12 months were used, divided into three experimental groups of five animais: Negative control group (GN): animais treated with 1 mL of 0.9% saline solution; Positive control group (GP): animais treated with 0.1 gram of allopathic ointment bascd on 35% Lauryl dimethyl benzyl ammonium chloridc and Aloe vera group (GA): animais treated with lg of 10% Aloe vera extract. Topical treatment was performed in the three experimental groups for 22 days every 24 hours, and skin fragmcnts were collected for morphologícal assessment on the lst, 8th, 15th and 22nd postoperative day. The three groups showed similar results in the evaluation on the lst, 8th, I5th day, differing only on the 22nd postoperative day, where the Aloe vera group had a lower amount of mononuclear cells, consequently edema. The Aloe vera group showed higher collagcn fiber deposition compared to the control and ointment groups used during the evaluation period. The effectiveness of 10% Aloe vera extract for the treatment of wounds in sheep was confirmed through microscopic evaluation, mdicating a good therapeutic effect of the healing process