https://repositorio.uema.br/jspui/handle/123456789/1975 Mon, 21 Sep 2026 21:43:24 GMT 2026-09-21T21:43:24Z https://repositorio.uema.br/jspui/handle/123456789/6822 Título: Ciência em tirinhas: explorando as ISTs na promoção da alfabetização científica por meio das histórias em quadrinhos Abstact: This undergraduate thesis investigated how the production of comic strips, integrated into an investigative teaching sequence, can contribute to the promotion of scientific literacy among 8th-grade students at the José Miranda Braz Municipal School in Zé Doca, Maranhão state. The qualitative research was based on the principles of Inquiry-Based Learning (IB) and used the Scientific Literacy Indicators as analytical frameworks. The sequence was organized into stages involving problematization, investigation, systematization, and communication of knowledge about Sexually Transmitted Infections (STIs), themes chosen for their social and formative relevance and the need to demystify taboos among adolescents. Data collection included field notes and analysis of the comic strips created by the students on the Pixton platform. The results showed that the creation of the comics enhanced the understanding of scientific concepts, stimulated argumentation, favored the social contextualization of STIs, and enabled the creative expression of hypotheses and explanations. Attributes related to scientific, social, and interaction indicators were identified, demonstrating that students mobilized knowledge, built cause-and-effect relationships, and understood the social implications of science. Despite the progress achieved, the project implementation process presented some challenges. Among them, the limitation of the school's technological infrastructure stood out, as it did not have sufficient equipment to serve all participants, especially for the final activity. Due to this deficiency, it was necessary for the students to travel to the campus of the Universidade Estadual do Maranhão (UEMA) in Zé Doca, where it was possible to use the computer lab and ensure the execution of the planned activities. In addition, difficulties related to transportation to the university, the students' initial apprehension about addressing the topic, as well as absences, dropouts, and limitations in using the digital platform used throughout the project were also observed. It is concluded that the use of comics as a teaching resource, combined with Inquiry-Based Education, constitutes an effective tool to promote engagement, critical thinking, and scientific literacy, especially when articulated with contextualized and digitally mediated practices. Tue, 30 Jun 2026 00:00:00 GMT https://repositorio.uema.br/jspui/handle/123456789/6822 2026-06-30T00:00:00Z https://repositorio.uema.br/jspui/handle/123456789/6821 Título: Contribuição ao conhecimento da flora nativa de Zé Doca-MA: um levantamento florístico-taxonômico da família Malvaceae Abstact: The Malvaceae family is widely distributed throughout tropical and subtropical regions, standing out for its ecological, economic, and taxonomic relevance. In the state of Maranhão, especially in ecological transition areas such as the municipality of Zé Doca, significant gaps in floristic knowledge still exist, reinforcing the need for systematic studies focused on the identification and cataloging of the local flora. In this context, the present study aimed to contribute to the knowledge of the flora of Zé Doca, Maranhão, through a floristic-taxonomic survey of the Malvaceae family. Collections were carried out in different environments, including native vegetation areas, transition zones, urban spaces, and peri-urban areas, encompassing a diversity of ecological conditions. Botanical material was collected, and taxonomic identification was performed based on specialized literature and updated botanical databases. As a result, 10 species belonging to different genera of the Malvaceae family were recorded, exhibiting varied growth habits, including herbs, shrubs, subshrubs, and trees. Most species showed wide geographic distribution throughout Brazilian territory and lack of endemism, indicating a strong influence of anthropogenic processes, such as cultivation and dispersal associated with human activities. In addition, an identification key for the recorded species was developed, contributing to regional taxonomic recognition. The results demonstrate that the local floristic composition reflects both the presence of typical tropical environment elements and the influence of anthropization, characterizing a scenario of high ecological plasticity. Thus, this study contributes to filling gaps in the knowledge of Maranhão flora, providing support for future research in botany, conservation, and environmental education. Thu, 25 Jun 2026 00:00:00 GMT https://repositorio.uema.br/jspui/handle/123456789/6821 2026-06-25T00:00:00Z https://repositorio.uema.br/jspui/handle/123456789/6817 Título: RNAs não codificantes no câncer de vulva: revisão sistemática de potenciais biomarcadores associados ao diagnóstico e prognóstico Abstact: Vulvar cancer (VC) is a rare gynecological neoplasm characterized by etiological and molecular heterogeneity, particularly between human papillomavirus (HPV)-associated and HPV- independent tumors. In this context, non-coding RNAs (ncRNAs) have been investigated because of their involvement in gene regulation and tumor progression and their possible use as biomarkers. This study aimed to identify and synthesize the available evidence on ncRNAs associated with VC, considering their biological roles and diagnostic and prognostic potential. A systematic literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) recommendations and registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD420261406196. Searches were performed in PubMed, Scopus, Web of Science, and Latin American and Caribbean Literature in Health Sciences (LILACS), considering studies published between 2010 and 2025. A total of 238 records were identified, of which 78 were removed as duplicates. After screening 160 records and assessing 19 full-text articles, eight studies were included in the qualitative synthesis. Five studies primarily investigated microRNAs (miRNAs), two examined long non-coding RNAs (lncRNAs), and one analyzed circular RNAs (circRNAs). Among the main findings, reduced expression of miR-30c and let- 7a was related to increased HMGA2 expression and tumor invasiveness; miR-223-5p and miR- 19b-1-5p showed lower expression in tumors with lymph node metastasis; and increased miR- 182-5p expression promoted proliferation, migration, invasion, and epithelial-mesenchymal transition. The lncRNAs MALAT1 and MEG3 and a set of circulating miRNAs showed potential to distinguish vulvar squamous cell carcinoma (VSCC) from non-tumor samples or precursor lesions. In addition, the UCA1/miR-103a/WEE1 axis was associated with cisplatin resistance, whereas circRNAs presented exploratory findings related to HPV-positive tumors. It is concluded that ncRNAs may contribute to the biological and clinical characterization of VC, although their application as biomarkers requires validation in larger and independent studies. Thu, 02 Jul 2026 00:00:00 GMT https://repositorio.uema.br/jspui/handle/123456789/6817 2026-07-02T00:00:00Z https://repositorio.uema.br/jspui/handle/123456789/6056 Título: Wattpad como ferramenta para a formação de leitores juvenis na era digital Abstact: Wattpad emerges as an innovative tool that redefines the way contemporary readers, especially young people, are formed and engaged. More than expanding access to reading, the platform promotes a type of digital-literary literacy in which the act of reading is intertwined with practices of interaction, production, and sharing. The general objective of this study is to analyze Wattpad as a tool for the development of young readers in the digital age, considering the transformations of the book and reading practices in cyberspace. Regarding the specific objectives, the following stand out: to understand the transformation of the book from printed to digital format, situating it within the context of the information age; to discuss reading practices in cyberspace, considering changes in ways of reading and relating to literary texts in digital environments; and to examine Wattpad as a space that contributes to the consolidation of reading among young people. The methodology employed is characterized by a bibliographic and quantitative approach, which included the application of a questionnaire to frequent Wattpad users. This study is justified by the need to understand youth reading practices that take place outside school and institutional settings, especially in digital environments such as Wattpad, where reading occurs as an everyday experience integrated with leisure, identity, and digital sociability. For the construction of the theoretical framework, the studies of Chartier (1998) were considered, whose contributions make it possible to understand the historical trajectory of the book and reading practices, from manuscript to print and to digital media; Martino (2015), who analyzes languages and processes of meaning production in the networked digital environment; and Santaella (2006), who understands reading as a historically constructed cognitive model, conditioned by the technical means of production and circulation of signs. The results of this study show that Wattpad acts as a relevant formative environment for young readers by consolidating reading practices supported by regularity, emotional engagement, and long-term continuity. In addition, the data indicate that Wattpad expands young people’s literary repertoire by enabling frequent contact with different genres, styles, and narrative forms, contributing to the development of reading competencies. Wed, 01 Jan 2025 00:00:00 GMT https://repositorio.uema.br/jspui/handle/123456789/6056 2025-01-01T00:00:00Z