Avaliação macroscópica do processo de cicatrização em feridas induzidas experimentalmente, tratadas com Aloe vera em ovinos

Abstract

This research aimed to evaluate the healing effect of Aloe vera on induced wounds in sheep. Fifteen animals were divided equally into three experimental groups. The wounds were made in the right paralumbar fossa and the animals were submitted to the following treatments: Negative control group (GN): 1mL of saline solution (0.9%), Positive control group (GP): 1g of allopathic ointment based on Lauryl dimethyl benzyl ammonium (35%) and Aloe vera Group (GA): 1g of Aloe vera extract (10%). Wounds were evaluated for 22 consecutive days and measured every 24 hours. For macroscopic evaluation, the following were evaluated: hemorrhage, crust, granulation tissue, swelling, color, hair growth in the area adjacent to the wound and epithelialization. As for the average wound area, there was a statistically significant difference on the 8th day of measurement (p=0.042) between the Aloe vera group, with 1.397 cm², and the positive control group, with 2.09 cm², which demonstrates that the Aloe vera provided greater wound contraction early in the healing process. In the macroscopic evaluation, characteristics such as hemorrhagic spots, crusts and epithelialization were more satisfactory in the Aloe vera Group. In view of the results obtained, it can be inferred that the Aloe vera extract (10%) was effective for the treatment of skin wounds in sheep.