Avaliação do efeito terapêutico do uso de pimobendan e lisinopril em cães com Degeneração Mixomatosa da Valva Mitral (DMVM)

Abstract

Mitral Valve Myxomatous Degeneration (VMMD) is the main heart disease that affects elderly and small dogs. As the changes can be identified through the echocardiogram, the electrocardiogram and the diagnostic test, the non-invasive diagnostic modalities, which can early detect this change. The objective of this work is to identify the therapeutic effects of pimobendan and lisinopril in dogs with stage B2 myxomatous mitral valve degeneration. Five animals were divided into two groups. With the first training for two previous years) of stage B2 DMVM treated with pimobendan (Gpim and the second with two later years of study of stage B2 DMVM treated with lisinopril (Glis). different at 20 days, blood samples were selected and hematological analysis, blood pressure measurement and biochemical, electrocardiogram and echocardiogram exams were performed (B-mode, M-mode and Doppler) for cardiac evaluation in three moments. used, it was possible to observe better in the echocardiographic, radiographic and electrocardiographic findings. No significant changes were identified in the erythroluometric and biochemical variables. As variations in SBP values, keep within the normal value in M3 in the groups and a reduction was observed of the clinical manifestations, related to the manifestations. A comprehensive proposal is effective in both groups, even with high erations of two dogs affected by an associated pathology.